Text: 941-666-4638
Call: 941-666-4638Platelet-Rich Plasma (PRP) Research
Platelet-Rich Plasma (PRP) Research & Applications
PRP and Hyaluronic Acid for Bone Exposure Wounds
Treating wounds with exposed bone remains a complex challenge in lower-extremity surgery. Researchers at the University of Tor Vergata in Rome conducted a study to assess the effectiveness of Platelet-Rich Plasma (PRP) combined with Hyaluronic Acid (HA) dressings in promoting wound healing.
Study Overview
- Patients with post-traumatic bone exposure were treated with either HA dressings alone or a combination of HA and PRP.
- A total of 15 patients participated in the study.
Findings
- 73.3% of patients who received PRP and HA dressings achieved wound re-epithelialization within 8.1 weeks.
- Only 30% of patients treated with HA alone experienced similar healing progress.
- Results demonstrated PRP’s ability to accelerate both soft- and hard-tissue repair.
Read More: Advances in Skin and Wound Care
PRP and Fat Grafting for Progressive Hemifacial Atrophy
Progressive hemifacial atrophy, or Parry-Romberg syndrome, is a rare degenerative condition that causes gradual loss of facial volume on one side of the face. Researchers explored the use of PRP in combination with autologous fat grafting to restore facial symmetry and improve tissue structure.
Study Approach
- PRP was extracted from a 9 mL blood sample and processed into platelet gel.
- The Coleman technique was used to strategically inject fat grafts into affected areas.
Results
- Patients experienced enhanced three-dimensional facial contouring.
- The combination of PRP and fat grafts significantly improved skin density, elasticity, and volume restoration.
PRP for Face and Neck Rejuvenation
PRP’s potential for skin revitalization and anti-aging was assessed in a study evaluating its effects on facial and neck rejuvenation over a three-month period.
Methodology
- 23 patients underwent three PRP injection sessions, administered one month apart.
- Blood samples were processed using a sterile Regen Lab Kit.
- Skin improvements were documented using dermoscopy, digital imaging, and medical imaging software.
Findings
- Notable improvements in skin texture, firmness, and elasticity were observed.
- PRP visibly reduced scars and signs of aging, enhancing skin vibrancy.
- No significant or long-term adverse effects were reported.
PRP and Platelet-Rich Fibrin Matrix (PRFM) for Skin Regeneration
A clinical study explored the regenerative properties of Platelet-Rich Fibrin Matrix (PRFM) when injected into the skin to promote collagen production, skin firmness, and vascular growth.
Study Parameters
- Four adult volunteers received PRFM injections into the deep dermis and subdermis.
- Full-thickness skin biopsies were collected at different intervals over a 10-week period.
Results
- Fibroblast activation and collagen production were detected within 7 days.
- By day 19, new blood vessels had formed, improving circulation and skin regeneration.
- PRFM also stimulated adipocyte growth, contributing to soft tissue augmentation and volume enhancement.
Advancing PRP in Regenerative Medicine
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